Linaclotide acetate CAS 851199-59-2(free base)
| CAS No. | 851199-59-2(free base) |
| Molecular Formula | C59H79N15O21S6 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Linaclotide acetate (CAS 851199-59-2(free base)), a certified reference material (molecular formula C59H79N15O21S6C2H4O2, MW 1586.78 g/mol) for analytical method development and quality control.
The molecular framework of Linaclotide acetate (C59H79N15O21S6C2H4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C59H79N15O21S6 C2H4O2 |
| Molecular Weight | 1586.78 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 15 |
| Sulfur Atoms | 6 |
Related Linaclotide Standards
- Linaclotide impurity 17 (CAS 1092457-78-7)
- Linaclotide impurity 35 (CAS 1207977-38-5)
- Linaclotide impurity 45 (CAS 1331835-31-4)
- Linaclotide impurity 43 (CAS 1422389-15-8)
- Linaclotide impurity 44 (CAS 1422389-16-9)
- Linaclotide (CAS 851199-59-2)
- Linaclotide Acetate - API Standards (CAS 851199-60-5)
- Cys1-Linaclotide Imidazolidione Impurity XTFA Salt (CAS CATO-C4X-21061)
Recommended Standards
- 1-ethyl-2-(phenylmethyl)ester,(1S,3aR,6aS)- (CAS 402958-21-8)
- 4-Bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1049730-37-1)
- rel-(1S,2S,5R)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid;hydrochloride (CAS 73804-69-0)
- 5-Chlorofuran-2-amine (CAS 13725-43-4)
- 2-(Aminomethyl)-N-phenylaniline (CAS 20877-84-3)
- N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2R)-2,3-dihydro-2-(1-piperidinyl)-1H-inden-1-yl]thiourea (CAS 1262616-57-8)
- 2-(2-(Difluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 960067-33-8)
- 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((3-nitropyridin-2-yl)amino)pyridin-2(1H)-one (CAS 338393-87-6)
- Methyl 4-(3,4-dichlorophenyl)-4-oxobutanoate (CAS 95652-74-7)
- DAPK Substrate Peptide (CAS 386769-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com